BDBM50022121 3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole::3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-34787)::CHEMBL284356

SMILES CC(C)c1[nH]c2ccccc2c1Cn1ccnc1

InChI Key InChIKey=NZXGMVRYQLENHC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50022121   

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  15nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of ram seminal vesicle CyclooxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthase by bioassay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed