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BDBM50022167 2-Amino-6-(indan-5-ylamino)-3H-pyrimidin-4-one::CHEMBL349592

SMILES: Nc1nc(Nc2ccc3CCCc3c2)cc(=O)[nH]1

InChI Key: InChIKey=YUPQFUXJUXRXOG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA topoisomerase III


(Bacillus subtilis)
BDBM50022167
PNG
(2-Amino-6-(indan-5-ylamino)-3H-pyrimidin-4-one | C...)
Show SMILES Nc1nc(Nc2ccc3CCCc3c2)cc(=O)[nH]1
Show InChI InChI=1S/C13H14N4O/c14-13-16-11(7-12(18)17-13)15-10-5-4-8-2-1-3-9(8)6-10/h4-7H,1-3H2,(H4,14,15,16,17,18)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration producing 50% inhibition of Bacillus subtilis DNA topoisomerase III in the presence of dATP using DNA Polymerase assay


J Med Chem 29: 676-81 (1986)


Article DOI: 10.1021/jm00155a016
BindingDB Entry DOI: 10.7270/Q2MP528D
More data for this
Ligand-Target Pair