BDBM50023714 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-5-(3,4-dichloro-benzoylamino)-pentanoic acid::CHEMBL405237

SMILES Nc1nc(N)c2nc(CN(C=O)c3ccc(cc3)C(=O)NC(CCCNC(=O)c3ccc(Cl)c(Cl)c3)C(O)=O)cnc2n1

InChI Key InChIKey=FGQAWUDZBCAAOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023714   

TargetDihydrofolate reductase(Mus musculus (Mouse))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023714(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-ami...)
Affinity DataIC50:  56nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed