BDBM50024447 (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::CHEMBL17695::HETE-(+/-)5::HETE-5(S)

SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O

InChI Key InChIKey=KGIJOOYOSFUGPC-XTDASVJISA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50024447   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataKi:  3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataIC50:  7.70E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024447((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed