BDBM50027285 2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-1H-benzoimidazole-5-carboxamidine::CHEMBL101261

SMILES NC(=N)c1ccc(OCCOc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(N)=N)cc1

InChI Key InChIKey=BJXTWYLLSITRJP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50027285   

TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  2.73E+3nMAssay Description:Inhibition constant against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  2.73E+3nMAssay Description:Competitive reversible inhibition of bovine thrombin using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after 15 to 40 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition constant against human plasminogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  5.98E+3nMAssay Description:Inhibition constant against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlandular kallikrein(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  1.13E+4nMAssay Description:Competitive reversible inhibition of porcine pancreatic kallikrein using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027285(2-{4-[2-(4-Carbamimidoyl-phenoxy)-ethoxy]-phenyl}-...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition constant against UrokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed