BDBM50027475 (E)-1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one (3)::2,2'',4''-Trihydroxychalcone::CHEMBL148472
SMILES Oc1ccc(C(=O)\C=C\c2ccccc2O)c(O)c1
InChI Key InChIKey=MACMAADVRVVHBD-VMPITWQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50027475
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
Affinity DataIC50: 2.45E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University
Curated by ChEMBL
Guangxi Medical University
Curated by ChEMBL
Affinity DataIC50: 5.68E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair