BDBM50027677 CHEMBL3344387
SMILES N[C@@H](CC(=O)N1C[C@H](CO)[C@H](C1)c1ccc(Cl)cc1)Cc1ccc(Cl)cc1
InChI Key InChIKey=ZFSKJGRASNTEBX-NSISKUIASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50027677
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of human NMT1 R295Q/W297F/A452M/L453V/L462V/N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as subst...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells ...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Inhibition of human NMT1 N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA aft...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Inhibition of human NMT1 L495M mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins b...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 631nMAssay Description:Inhibition of human NMT1 using GSNKSKPKDASQRRR-NH2 as substrate by CPM fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) expressed in Escherichia coli Rosetta-2 cells using GSN...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human NMT1 using GSNKSKPKDASQRRR-NH2 as substrate by CPM fluorescence assayMore data for this Ligand-Target Pair