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BDBM50027835 7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one( am)::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one(desmethyldiazepam)::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one(nordiazepam)::7-chloro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one::CHEMBL523::DESMETHYLDIAZEPAM::Gen-Xene::Nordazepam::Tranxene

SMILES: Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI Key: InChIKey=AKPLHCDWDRPJGD-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027835   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Translocator protein


(Homo sapiens (Human))
BDBM50027835
PNG
(7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepi...)
Show SMILES Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1
Show InChI InChI=1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
KEGG

UniProtKB/SwissProt

DrugBank
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CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.40E+9n/an/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay


J Med Chem 39: 5246-56 (1997)

More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50027835
PNG
(7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepi...)
Show SMILES Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1
Show InChI InChI=1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.20E+5n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against PBR(peripheral benzodiazepine receptor) in normal rat brain homogenate


J Med Chem 40: 1726-30 (1997)

More data for this
Ligand-Target Pair