BDBM50030281 CHEMBL1870764

SMILES OC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1

InChI Key InChIKey=BIUCOFQROHIAEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50030281   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50030281(CHEMBL1870764)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of APE1 in human HeLa cells assessed as reduction in AP site cleavage 5'-[gamma-32P]CTCGCAAGUGGGTACCGA-3' as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50030281(CHEMBL1870764)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human APE1 after 25 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed