BDBM50031170 (S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentanoic acid 2,4-dichloro-benzylamide::CHEMBL129603

SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=CVQDOSPJHKPBQQ-AFGDWVFNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031170   

LigandPNGBDBM50031170((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50031170((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...)
Affinity DataIC50:  97nMAssay Description:In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed