BDBM50031589 CHEMBL3359179
SMILES NS(=O)(=O)c1c(F)c(F)c(SCCO)c(F)c1NC1CCCCCCC1
InChI Key InChIKey=ZUTOCUUMVDYVHW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 35 hits for monomerid = 50031589
Affinity DataKd: 5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.180nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: >2.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 3 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Inhibition of human carbonic anhydrase 5B at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 6 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Inhibition of human carbonic anhydrase 7 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by fluorescent thermal shi...More data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Inhibition of chimeric carbonic anhydrase 12 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by fluorescent thermal sh...More data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Inhibition of human carbonic anhydrase 13 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Inhibition of human carbonic anhydrase 14 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 730nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by isothermal titration ca...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 420nMAssay Description:Inhibition of human carbonic anhydrase 13 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 4.60E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
Affinity DataKd: 910nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
Affinity DataKd: <5nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 25 degC by stopped-flow kinetic in...More data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Inhibition of human carbonic anhydrase 13 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0100M-1s-1Assay Description:Binding affinity to CA7 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.000330M-1s-1Assay Description:Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKon: 0.0500M-1s-1Assay Description:Binding affinity to CA12 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.00770M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.90nMAssay Description:Binding affinity to CA7 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding affinity to CA12 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic th...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair