BDBM50031651 4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfonyl]-benzoic acid::CHEMBL80030

SMILES CN(C)CC(=C)C(=O)c1ccc(OS(=O)(=O)c2ccc(cc2)C(O)=O)cc1

InChI Key InChIKey=UPVWXHAZXKGELN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031651   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031651(4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfo...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of the Epidermal growth factor receptor activity in A431 membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031651(4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfo...)
Affinity DataIC50:  5.00E+4nMAssay Description:In vitro inhibition of the v-abl tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba

Curated by ChEMBL
LigandPNGBDBM50031651(4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of the c-src tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed