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BDBM50031907 CHEMBL2337245

SMILES: Cc1ccc(o1)-c1cc(C(=O)NCc2cccc(CNC(=O)c3cc(nc4ccccc34)-c3ccc(C)o3)c2)c2ccccc2n1

InChI Key: InChIKey=BZVLBOGYHROKAH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031907   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM50031907
PNG
(CHEMBL2337245)
Show SMILES Cc1ccc(o1)-c1cc(C(=O)NCc2cccc(CNC(=O)c3cc(nc4ccccc34)-c3ccc(C)o3)c2)c2ccccc2n1
Show InChI InChI=1S/C38H30N4O4/c1-23-14-16-35(45-23)33-19-29(27-10-3-5-12-31(27)41-33)37(43)39-21-25-8-7-9-26(18-25)22-40-38(44)30-20-34(36-17-15-24(2)46-36)42-32-13-6-4-11-28(30)32/h3-20H,21-22H2,1-2H3,(H,39,43)(H,40,44)
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.79E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...


J Med Chem 57: 9309-22 (2014)


Article DOI: 10.1021/jm500692u
BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
More data for this
Ligand-Target Pair