BDBM50032749 CHEMBL3355177

SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)Nc1cnn(c1)C1CCNCC1

InChI Key InChIKey=ILUOKEKSMZBBQY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032749   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032749(CHEMBL3355177)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of JNK3 in human SH-SY5Y cells assessed as reduction in c-Jun phosphorylation by Western blot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032749(CHEMBL3355177)
Affinity DataIC50:  25nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032749(CHEMBL3355177)
Affinity DataIC50:  679nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032749(CHEMBL3355177)
Affinity DataIC50:  23nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed