BDBM50032891 CHEMBL3342784
SMILES C[C@H](Nc1nccc(n1)N1C(=O)OC[C@]1(C)C1CC1)c1ccc(CN2CCC(N)CC2)c(F)c1
InChI Key InChIKey=CFXVZZKUNLNHGU-IVCQMTBJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50032891
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 376nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as inhibition of [3C]2-hydroxyglutarate formation after 45 mins by LC-MS biochemical assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using a-ketoglutarate as substrate by fluorescence biochemical assayMore data for this Ligand-Target Pair