BDBM50033061 27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-30-propyl-1,4,7,10,13,16,19,22,25,28,31undecaaza-cyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone::CHEMBL384726

SMILES CCC[C@H]1NC(=O)[C@@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](C)NC(=O)[C@@H](C)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](CO)N(C)C1=O)C(C)C

InChI Key InChIKey=UVAZRAAUMKLNAN-INJCWPFZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033061   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)
Affinity DataIC50:  48nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by rotamase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-2(Mus musculus)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)
Affinity DataIC50:  26nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)
Affinity DataIC50:  93nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed