BindingDB logo
myBDB logout

BDBM50033842 1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL172363

SMILES: COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1

InChI Key: InChIKey=OKYMMNZLKVUQRW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033842   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50033842
PNG
(1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetra...)
Show SMILES COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1
Show InChI InChI=1S/C26H36N2O2/c1-29-23-14-13-22-10-7-9-21(24(22)20-23)8-5-6-15-27-16-18-28(19-17-27)25-11-3-4-12-26(25)30-2/h3-4,11-14,20-21H,5-10,15-19H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8.83n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
In vitro binding affinity measured on serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.


J Med Chem 38: 942-9 (1995)


Article DOI: 10.1021/jm00006a013
BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50033842
PNG
(1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetra...)
Show SMILES COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1
Show InChI InChI=1S/C26H36N2O2/c1-29-23-14-13-22-10-7-9-21(24(22)20-23)8-5-6-15-27-16-18-28(19-17-27)25-11-3-4-12-26(25)30-2/h3-4,11-14,20-21H,5-10,15-19H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 92.8n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
In vitro binding affinity measured on sigma opioid receptor using [3H]-DTG as radioligand


J Med Chem 38: 942-9 (1995)


Article DOI: 10.1021/jm00006a013
BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50033842
PNG
(1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetra...)
Show SMILES COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1
Show InChI InChI=1S/C26H36N2O2/c1-29-23-14-13-22-10-7-9-21(24(22)20-23)8-5-6-15-27-16-18-28(19-17-27)25-11-3-4-12-26(25)30-2/h3-4,11-14,20-21H,5-10,15-19H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 50.9n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
In vitro binding affinity measured on dopamine receptor D2 using [3H]-spiroperidol as radioligand.


J Med Chem 38: 942-9 (1995)


Article DOI: 10.1021/jm00006a013
BindingDB Entry DOI: 10.7270/Q2SQ8ZD0
More data for this
Ligand-Target Pair