BDBM50033882 CHEMBL3358174

SMILES Cc1ncc(n1CCNC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)[N+]([O-])=O

InChI Key InChIKey=HLORWOKIAJHNMK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033882   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033882(CHEMBL3358174)
Affinity DataIC50:  44nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033882(CHEMBL3358174)
Affinity DataIC50:  131nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033882(CHEMBL3358174)
Affinity DataIC50:  160nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50033882(CHEMBL3358174)
Affinity DataIC50:  640nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed