BDBM50034142 CHEMBL16863::N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-formamide

SMILES CN1[C@@H]2CCC3C4CC[C@H](N(CCC(C)(C)C)C=O)[C@@]4(C)CCC3[C@@]2(C)CCC1=O

InChI Key InChIKey=HAPCTYIHYYGVQQ-AXXVANDLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034142   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034142(CHEMBL16863 | N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034142(CHEMBL16863 | N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7...)
Affinity DataIC50:  171nMAssay Description:In vitro inhibition of DHT (dihydrotestosterone) on proliferation of androgen-sensitive cancer Schionogi (SC-3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034142(CHEMBL16863 | N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed