BDBM50034474 4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL283941

SMILES Cc1cc(NS(=O)(=O)c2ccc(N)cc2)on1

InChI Key InChIKey=KBLGZYOVYFTAOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034474   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034474(4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50:  2.80E+4nMAssay Description:Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034474(4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50:  2.80E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed