BDBM50034864 (S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamino)-pentanoic acid::CHEMBL46081

SMILES OC(=O)CC[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O

InChI Key InChIKey=VRSUMLWKSZXAQR-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034864   

TargetNeprilysin(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50034864((S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamino)-p...)
Affinity DataIC50:  550nMAssay Description:Inhibition of recombinant human NEP expressed in insect cells preincubated for 1 hr using Cys(PT14)-Arg-Arg-Leu-Trp-OH as substrate and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034864((S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamino)-p...)
Affinity DataIC50:  99nMAssay Description:In vitro inhibition of rat neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed