BDBM50035471 2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-acetamide::CHEMBL38521
SMILES CN([C@H](CN1CCCC1)c1cccc(c1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=BNAKCEFXXMHXDQ-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50035471
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity for delta opioid receptor in guinea pig brain membranes, using 2 nM [3H]-DPDPE as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 2.40nMAssay Description:Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity for mu opioid receptor in guinea pig brain membranes, using 2 nM [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity of compound towards mu receptor by using radioligand [3H]-DAMG0 on guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity of compound towards delta receptor by using radioligand [SHIDPDPE on guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Binding affinity of compound towards kappa receptor by using radioligand [3H]-U-69,593 on guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Binding affinity kappa opioid receptor in guinea pig brain membranes, using 1 nM [3H]-U69,593 as radioligandMore data for this Ligand-Target Pair