BDBM50036356 (Z)-6-{2-[2-(2-Cyano-4-fluoro-phenyl)-1,1-dimethyl-ethyl]-4-pyridin-3-yl-[1,3]dioxan-5-yl}-hex-4-enoic acid::CHEMBL159851

SMILES CC(C)(Cc1ccc(F)cc1C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1

InChI Key InChIKey=OQZXYHKQDDFAIU-ARJAWSKDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036356   

TargetProstacyclin synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036356((Z)-6-{2-[2-(2-Cyano-4-fluoro-phenyl)-1,1-dimethyl...)
Affinity DataIC50:  7.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed