BDBM50037484 (6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL114163

SMILES CCCCCCCCN1CC[C@@]2(C)[C@H](C)C1Cc1ccc(O)cc21

InChI Key InChIKey=KRRIOBULVTVQLP-UCLFCPHBSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50037484   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037484((6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  2.80nMAssay Description:Inhibition against sigma receptor using displacement of 3 nM [3H]pentazocine in homogenate of guinea pig brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037484((6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  160nMAssay Description:Inhibition against mu receptor from displacement studies using 0.5 nM [3H]-DAMGO in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037484((6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  522nMAssay Description:Inhibition against mu receptor using [3H]DAMGO in homogenate of rat brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037484((6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  1.59E+3nMAssay Description:Inhibition against delta receptor from displacement studies using 1.5 nM [3H]DPDPE in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037484((6S,11S)-6,11-Dimethyl-3-octyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  2.27E+3nMAssay Description:Inhibition against kappa receptor from displacement studies using 1.5 nM [3H]U-69593 in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed