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BDBM50038423 CHEMBL3361128

SMILES: Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O

InChI Key: InChIKey=HCBULGQMULJTCM-RIYZIHGNSA-N

Data: 18 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50038423   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-dependent protein kinase (PKA)


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant PRKACA (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Aurora kinase B


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 735n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AURKB (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
p21-Activated kinase 2 (PAK2)


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant PAK2 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 1


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant MAPK1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant IGF1R (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant EGFR (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha (CK1 Alpha)


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 7.88E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant CK1 alpha1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 3.86E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AKT1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Aurora kinase B


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/an/a 3.10n/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Binding affinity to AURKB (unknown origin)


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/an/a 1.30n/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Binding affinity to AURKA (unknown origin)


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 2.68E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant PKC alpha (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Nek1


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.15E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant NEK1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 5.96E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant KDR (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 5.19E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT4 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Aurora-C


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 4.75E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AURKC (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 4.04E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant PDGFR alpha (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 3.70E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 2.63E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant GSK-3 beta (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.34E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AURKA (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (human))
BDBM50038423
PNG
(CHEMBL3361128)
Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant PLK1 (unknown origin) after 60 mins by z'-lyte kinase assay


Eur J Med Chem 89: 310-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.044
BindingDB Entry DOI: 10.7270/Q2JQ12NJ
More data for this
Ligand-Target Pair