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BDBM50040082 CHEMBL307023::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-iodo-6-methoxy-3-sulfamoyl-benzamide (iodosulpride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide(iodosulpiride)

SMILES: CCN1CCC[C@H]1CNC(=O)c1c(I)c(ccc1OC)S(N)(=O)=O

InChI Key: InChIKey=HCKMONAVUWHQOT-JTQLQIEISA-N

Data: 1 KI  1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040082   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040082
PNG
(CHEMBL307023 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(I)c(ccc1OC)S(N)(=O)=O
Show InChI InChI=1S/C15H22IN3O4S/c1-3-19-8-4-5-10(19)9-18-15(20)13-11(23-2)6-7-12(14(13)16)24(17,21)22/h6-7,10H,3-5,8-9H2,1-2H3,(H,18,20)(H2,17,21,22)/t10-/m0/s1
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GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.5n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition constant against dopamine receptor D2 in rat


J Med Chem 36: 221-8 (1993)


Article DOI: 10.1021/jm00054a005
BindingDB Entry DOI: 10.7270/Q2TT4Q10
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040082
PNG
(CHEMBL307023 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(I)c(ccc1OC)S(N)(=O)=O
Show InChI InChI=1S/C15H22IN3O4S/c1-3-19-8-4-5-10(19)9-18-15(20)13-11(23-2)6-7-12(14(13)16)24(17,21)22/h6-7,10H,3-5,8-9H2,1-2H3,(H,18,20)(H2,17,21,22)/t10-/m0/s1
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.5n/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissue


J Med Chem 33: 171-8 (1990)


Article DOI: 10.1021/jm00163a029
BindingDB Entry DOI: 10.7270/Q2280860
More data for this
Ligand-Target Pair