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BDBM50040461 (S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-heptanoylamino)-pentanoic acid::(S)-5-(4-Benzyl-phenylsulfanyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid::CHEMBL434630

SMILES: OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1

InChI Key: InChIKey=BLFSPSZATDQQMK-NDEPHWFRSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040461   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Group VII phospholipase A2


(Sus scrofa)
BDBM50040461
PNG
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1
Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
Compound was tested for in vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and micellar substrate with deoxycholate (DOC)


J Med Chem 37: 557-9 (1994)


Article DOI: 10.1021/jm00031a001
BindingDB Entry DOI: 10.7270/Q28W3CB7
More data for this
Ligand-Target Pair
Group VII phospholipase A2


(Sus scrofa)
BDBM50040461
PNG
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1
Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate


J Med Chem 37: 557-9 (1994)


Article DOI: 10.1021/jm00031a001
BindingDB Entry DOI: 10.7270/Q28W3CB7
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (human))
BDBM50040461
PNG
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1
Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
Compound was tested for in vitro activity against s-phospholipase A2 (s-PLA2) isolated from human platelets


J Med Chem 37: 557-9 (1994)


Article DOI: 10.1021/jm00031a001
BindingDB Entry DOI: 10.7270/Q28W3CB7
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)