BDBM50040796 CHEMBL3353192::US10023562, Example 85::US10544133, Example 85::US9657009, 85
SMILES CC(C)Nc1cc(Nc2ncc(cc2C)C#N)ncc1C(=O)NC[C@@H](F)C(C)(C)O
InChI Key InChIKey=FMBDHUSEBGYMBK-QGZVFWFLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50040796
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery
Curated by ChEMBL
Nimbus Discovery
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery
Curated by ChEMBL
Nimbus Discovery
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery
Curated by ChEMBL
Nimbus Discovery
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery
Curated by ChEMBL
Nimbus Discovery
Curated by ChEMBL
Affinity DataIC50: 3.60nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair