BDBM50040913 1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quinoxaline-6,8-dione::CHEMBL266255

SMILES O=C1NC(=O)c2cc3N(CCN(c4ccccc4)c3cc12)c1ccccc1

InChI Key InChIKey=DNRPTTQOSZQOGJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040913   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory activity was determined against protein kinase A (PKA) of rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed