BDBM50042420 3-{4-Methyl-2-[4-methyl-2-(toluene-4-sulfonylamino)-pentanoylamino]-pentanoylamino}-2-oxo-pentanoic acid ethyl ester::CHEMBL3142935

SMILES CCOC(=O)C(=O)[C@H](CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=AWPCEFCYGSDQEV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042420   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042420(3-{4-Methyl-2-[4-methyl-2-(toluene-4-sulfonylamino...)
Affinity DataKi:  260nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042420(3-{4-Methyl-2-[4-methyl-2-(toluene-4-sulfonylamino...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042420(3-{4-Methyl-2-[4-methyl-2-(toluene-4-sulfonylamino...)
Affinity DataKi:  6.90E+4nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed