BDBM50042857 CHEMBL3354494

SMILES COc1ccc(cc1C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)C(=O)NCc1ccnc(n1)C#N

InChI Key InChIKey=WCQQOAFZCDVMEP-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042857   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant Cathepsin S using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human recombinant Cathepsin B using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of human recombinant Cathepsin C using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed