BDBM50042978 (E)-1-(2-hydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one::(E)-3-(4-hydroxyphenyl)-1-(2-hydroxyphenyl)-2-propen-1-one::3-(4-Hydroxy-phenyl)-1-(2-hydroxy-phenyl)-propenone::CHEMBL126804::Chalcone 3::US11866416, Compound SN-II-113
SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1
InChI Key InChIKey=FGPJTMCJNPRZGF-JXMROGBWSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50042978
Affinity DataIC50: 2.42E+4nMT: 2°CAssay Description:Binding of chalcone 4 and chlcone 1 to CSCL12 was examined by monitoring changes in the emission intensity of intrinsic Trp fluorescence of the chemo...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation
US Patent
Uab Research Foundation
US Patent
Affinity DataIC50: 2.13E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University
Curated by ChEMBL
Guangxi Medical University
Curated by ChEMBL
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair