BDBM50043018 CHEMBL3355028::US9718825, Example 63

SMILES NCCCOc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=YRZXTWXYARRXKW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043018   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)
Affinity DataIC50: <1.20nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)
Affinity DataIC50: <1.20nMAssay Description:Inhibition of SGK1 (unknown origin) assessed as substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant SGK1 (unknown origin) expressed in U2OS cells by cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed