BDBM50043687 CHEMBL3355547::US9416132, 8-49

SMILES CO[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(OC(F)(F)F)c3)c2n1

InChI Key InChIKey=JOUAHPWBRPLGSY-SHTZXODSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043687   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM50043687(CHEMBL3355547 | US9416132, 8-49)
Affinity DataIC50:  378nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043687(CHEMBL3355547 | US9416132, 8-49)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of Pim2 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM50043687(CHEMBL3355547 | US9416132, 8-49)
Affinity DataIC50:  378nMAssay Description:Inhibition of Pim1 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed