BDBM50043977 CHEMBL543434::CHEMBL91628::N,N'-Bis-(3-ethyl-phenyl)-N-methyl-guanidine

SMILES CCc1cccc(c1)N=C(N)N(C)c1cccc(CC)c1

InChI Key InChIKey=XOUNMBBCBFFCKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043977   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043977(CHEMBL543434 | CHEMBL91628 | N,N'-Bis-(3-ethyl-phe...)
Affinity DataIC50:  82nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043977(CHEMBL543434 | CHEMBL91628 | N,N'-Bis-(3-ethyl-phe...)
Affinity DataIC50:  82nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed