BDBM50044561 CHEMBL3222137

SMILES OC(=O)CCc1cc(ccc1OCc1ccc2c(O)noc2c1)C(=O)c1ccc(OC2CCCC2)cc1O

InChI Key InChIKey=DALCQQSLNPLQFZ-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044561   

TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  1.54E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 acyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A3(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  2.55E+3nMAssay Description:Substrate inhibition of human UGT1A3-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  3.64E+3nMAssay Description:Substrate inhibition of human UGT1A8-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  4.67E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A3(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  1.35E+4nMAssay Description:Substrate inhibition of human UGT1A3-mediated T-5224 acyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of AP-1 bZIP domain DNA binding activity (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of AP-1 (unknown origin) expressed in TPA-stimulated mouse NIH3T3 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed