BDBM50044561 CHEMBL3222137
SMILES OC(=O)CCc1cc(ccc1OCc1ccc2c(O)noc2c1)C(=O)c1ccc(OC2CCCC2)cc1O
InChI Key InChIKey=DALCQQSLNPLQFZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50044561
Affinity DataKi: 1.54E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 acyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC meth...More data for this Ligand-Target Pair
Affinity DataKi: 2.55E+3nMAssay Description:Substrate inhibition of human UGT1A3-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
Affinity DataKi: 3.64E+3nMAssay Description:Substrate inhibition of human UGT1A8-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
Affinity DataKi: 4.67E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+4nMAssay Description:Substrate inhibition of human UGT1A3-mediated T-5224 acyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC meth...More data for this Ligand-Target Pair
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AP-1 bZIP domain DNA binding activity (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch
Curated by ChEMBL
University Of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AP-1 (unknown origin) expressed in TPA-stimulated mouse NIH3T3 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair