BDBM50045359 (20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-4-yl ester; hydrochloride::CHEMBL539032

SMILES CCC1(OC(=O)CN)C(=O)OCc2c1cc1-c3nc4cccc(N)c4cc3Cn1c2=O

InChI Key InChIKey=GIRLBXKRNUXODQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045359   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045359((20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dio...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045359((20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dio...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed