BDBM50045922 5-[2-(3-Hydroxy-phenyl)-vinyl]-benzene-1,3-diol::CHEMBL99852

SMILES Oc1cccc(\C=C\c2cc(O)cc(O)c2)c1

InChI Key InChIKey=QUGCFFKLKWANMQ-SNAWJCMRSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045922   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50045922(5-[2-(3-Hydroxy-phenyl)-vinyl]-benzene-1,3-diol | ...)
Affinity DataIC50:  1.70E+4nMAssay Description:Tested in vitro for the inhibition of protein-tyrosine kinase p56lck using angiotensin I (1.2 mM) and [gamma-32P]-ATP (50 pM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50045922(5-[2-(3-Hydroxy-phenyl)-vinyl]-benzene-1,3-diol | ...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50045922(5-[2-(3-Hydroxy-phenyl)-vinyl]-benzene-1,3-diol | ...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx preincubated for 6 mins followed by AITC addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed