BDBM50048319 (S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl-1-oxo-butylamino)-cyclopentanecarbonyl]-amino}-propionic acid::(S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl-butyrylamino)-cyclopentanecarbonyl]-amino}-propionic acid::3-Biphenyl-4-yl-2-{[1-(2-mercapto-3-methyl-butyrylamino)-cyclopentanecarbonyl]-amino}-propionic acid::CGS-30084::CHEMBL64081

SMILES CC(C)[C@H](S)C(=O)NC1(CCCC1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=HPOHWZYSJMJZSA-VXKWHMMOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048319   

TargetEndothelin-converting enzyme 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50:  77nMAssay Description:In vitro inhibition of human Endothelin converting Enzyme-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50:  16nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50:  139nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelin-converting enzyme 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50:  77nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed