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BDBM50048875 CHEMBL431343::N-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-N'-phenyl-ethane-1,2-diamine

SMILES: COc1cccc2C(CCCNCCNc3ccccc3)CCCc12

InChI Key: InChIKey=KXJWNZITOQQZAO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048875   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50048875
PNG
(CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...)
Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12
Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
14n/an/an/an/an/an/an/an/a



Universit£ di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin


J Med Chem 39: 176-82 (1996)


Article DOI: 10.1021/jm950409c
BindingDB Entry DOI: 10.7270/Q2765G0J
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50048875
PNG
(CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...)
Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12
Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
265n/an/an/an/an/an/an/an/a



Universit£ di Bari

Curated by ChEMBL


Assay Description
Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane


J Med Chem 39: 176-82 (1996)


Article DOI: 10.1021/jm950409c
BindingDB Entry DOI: 10.7270/Q2765G0J
More data for this
Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50048875
PNG
(CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...)
Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12
Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.13E+3n/an/an/an/an/an/an/an/a



Universit£ di Bari

Curated by ChEMBL


Assay Description
Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M


J Med Chem 39: 176-82 (1996)


Article DOI: 10.1021/jm950409c
BindingDB Entry DOI: 10.7270/Q2765G0J
More data for this
Ligand-Target Pair