BDBM50049064 CHEMBL3319498::US10730833, Compound 11a::US9969686, Compound 11a

SMILES Clc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1

InChI Key InChIKey=IDDUUHHPSKLXPI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049064   

TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049064(CHEMBL3319498 | US10730833, Compound 11a | US99696...)
Affinity DataEC50:  93nMAssay Description:Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049064(CHEMBL3319498 | US10730833, Compound 11a | US99696...)
Affinity DataEC50:  93nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049064(CHEMBL3319498 | US10730833, Compound 11a | US99696...)
Affinity DataEC50:  93nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails US Patent