BDBM50049257 Azepan-(2Z)-ylideneamine::CHEMBL315857::CHEMBL543752

SMILES NC1=NCCCCC1

InChI Key InChIKey=GTLJSJNKRLFVSJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50049257   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  5.40E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed