BDBM50049302 8-ethyl-8-hydroxy-15-(4-hydroxymethyl-1-pyridiniumylmethyl)-(8S)-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[3,2-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12-dione::CHEMBL159322

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4c(C[n+]4ccc(CO)cc4)c3Cn1c2=O

InChI Key InChIKey=QIEUCEQCSGDUDQ-LJAQVGFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049302   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049302(8-ethyl-8-hydroxy-15-(4-hydroxymethyl-1-pyridinium...)
Affinity DataIC50:  340nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed