BDBM50049338 CHEMBL353093::N-[1-{[Acetyl-(2-methoxy-benzyl)-amino]-methyl}-2-(1H-indol-3-yl)-ethyl]-2-(4-benzyl-piperazin-1-yl)-acetamide

SMILES COc1ccccc1CN(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(Cc2ccccc2)CC1)C(C)=O

InChI Key InChIKey=FAIPAHUUUZBARZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049338   

TargetSubstance-P receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049338(CHEMBL353093 | N-[1-{[Acetyl-(2-methoxy-benzyl)-am...)
Affinity DataIC50:  0.880nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in guinea pig brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049338(CHEMBL353093 | N-[1-{[Acetyl-(2-methoxy-benzyl)-am...)
Affinity DataIC50:  0.880nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in guinea pig brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049338(CHEMBL353093 | N-[1-{[Acetyl-(2-methoxy-benzyl)-am...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in rat brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed