BDBM50049904 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL353764::TCMDC-124301

SMILES Nc1nc(N)c2c3cc[nH]c3ccc2n1

InChI Key InChIKey=AMQWKZUAOLLUPP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049904   

TargetDihydrofolate reductase(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human recombinant DHFR preincubated for 2 mins followed by substrate addition in presence of dihydrofolateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Candida albicans)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  23nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50049904(7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL3...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed