BDBM50049906 7-tert-Butyl-8-ethyl-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine::CHEMBL369258::TCMDC-137306

SMILES CCc1cc2c(ccc3nc(N)nc(N)c23)n1C(C)(C)C

InChI Key InChIKey=UOAQMUMUMLWAOF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049906   

TargetDihydrofolate reductase(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049906(7-tert-Butyl-8-ethyl-7H-pyrrolo[3,2-f]quinazoline-...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed