BDBM50050520 Boronic acid derivative::CHEMBL63406::US11096924, DASH-inhibitors 4175::US11559537, Compound 4175

SMILES CC(C)(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=YLQGXGBOYJWXBT-JGVFFNPUSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50050520   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  60nMAssay Description:In vitro for inhibition of Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8/9(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  12nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  1.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  1.60E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  8.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  3.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHomeobox protein PKNOX1(Human)
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  2.40E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 8/9(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  1.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  5.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  1.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  1.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  88nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  32nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  24nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50:  5.10E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent