BDBM50050578 5-Methyl-2-(2-propoxy-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL42435

SMILES CCCOc1ccccc1-c1nc2scc(C)c2c(=O)[nH]1

InChI Key InChIKey=XNNVIRKXMRBRIZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050578   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050578(5-Methyl-2-(2-propoxy-phenyl)-3H-thieno[2,3-d]pyri...)
Affinity DataEC50:  700nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050578(5-Methyl-2-(2-propoxy-phenyl)-3H-thieno[2,3-d]pyri...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed