BDBM50050794 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL25344
SMILES COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1
InChI Key InChIKey=FEJVSJIALLTFRP-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50050794
Affinity DataKi: 6nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity against human Endothelin A receptor; orally active in vivo at 30 mg/kg, poMore data for this Ligand-Target Pair
Affinity DataKi: 371nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity against human Endothelin B receptor; orally active in vivo at 30 mg/kg, poMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair