BDBM50051300 (6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-m-tolyl-amine::CHEMBL307062

SMILES Cc1cccc(Nc2ncnc3[nH]c4CCCCc4c23)c1

InChI Key InChIKey=CEYLERMRBKSAND-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051300   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051300((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50:  820nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051300((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051300((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of tyrosine kinase c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051300((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051300((6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed